Alopecia Areata (AA) is characterized by reversible hair loss where the hair follicle is preserved. Approximately 2% of the general population is affected by this condition. AA typically manifests itself by hair loss involving the scalp, eyebrows, beard, and/or body. It can appear as small to large circles of hair loss to total loss of hair in the scalp and body hair.
Available treatments include topical agents, such as minoxidil, corticosteroids (injections, oral or topical), phototherapy, dietary modifications and topical immune therapy. However, these treatments have mostly a temporary and inconsistent effect.
A clinical research study now underway in Montreal is seeking adult volunteers who have lost at least 50% of the hair on their head to determine the safety, tolerability, and efficacy of an investigational treatment called a monoclonal antibody — a substance that attaches itself to other substances or cells in the body. By doing so, it can modify the way these substances or cells act in the body.